Part of this certainty was attributable to the discomfort I felt with the culture of the lab itself. Labs at that time were not like the ones today. Not that I cared a terrible amount about my colleagues’ lives, the things they were interested in outside of the office, but there was at work a kind of conservatism, a fixation on neatness, that I found difficult and dispiriting. In those days science considered itself the realm of gentlemen. This was the era, after all, of Linus Pauling and J. Robert Oppenheimer, both of them exceptional, of course, but not exempt from having to dress a certain way, or from being able to perform at cocktail parties, or from pursuing romance. Genius was no excuse for social ineptitude, the way it is today, when a certain refusal to acquire the most basic social skills or an inability to dress properly or feed oneself is generously perceived as evidence of one’s intellectual purity and commitment to the life of the mind.

  But this was not how it always was. Then, it was difficult to ignore one’s colleagues’ extraoffice activities and interests because one was expected to be appropriate in one’s own. People spoke of the Turks approvingly not only because they had done well in school and were, so it was said, quick-minded and obedient and thoughtful, but because they were so presentable. Both had wives who had gone to Radcliffe, both came from well-known East Coast families, both were handsome enough and well dressed. They were very earnest. They were convinced that what they were doing was serious and important work—and so was I—but they were the sort of men for whom humor was to be practiced only at the appropriate events (parties, dinners, etc.) and then only within a very limited range. Except to Europe with their parents (and, I suppose, with the army in wartime, which hardly counts), neither of them had traveled, and neither of them longed to. Their friends were people like themselves, and they hired people like themselves—Ulliver and Nesser compensated for their strange Scandinavian surnames with their nicknames, which were Skip and Trip—and their lives were the lab to their homes in Cambridge or Newton and then back. People like Fat Irish may never have thought beyond a life of emptying mice cages and swabbing urine from the lab floors, but in their own way the Turks were as limited, as unimaginative: they assumed they would make a great contribution to mankind, and that is a faultless goal, I suppose, but the process itself never seemed as compelling to them as the outcome was, nor as the fantasy of having their name appended to whatever it is they dreamed of inventing or solving or fixing. I had gone into science for its adventure, but to them, adventure was something to be endured, not sought, on the road to inevitable greatness.

  II.

  It was not until I had been working at the lab for six months that I finally had my chance to meet Smythe. I had seen him before, of course, but only in glimpses: in newspapers, in magazines, as he ran into the lab to talk with Brassard and Fitch or to grab a piece of paper or a journal from his otherwise worrisomely tidy desk before leaving again for the world outside his lab. A few of my professors would occasionally ask me about him, jealous: What did he have me doing in that lab? What was he doing? I always told the truth, and this was boring and opaque enough to stop their questions: I cut open mice; I didn’t know. Had I known what I thought about him, had I admired him and wished to protect his work, I would have lied and made my own work sound more fascinating.

  One day, however, Brassard stopped by my counter as I was grating mice spleens. “Smythe left this for you,” he said, placing an envelope by my elbow. He was disapproving, but he was always disapproving. I took off my gloves and opened the envelope, a regular business-sized envelope with my name typed on the front. Inside was a letter on onionskin—also typed, so poorly I assumed Smythe had done so himself—inviting me to dinner that Friday, at 6:30 p.m. He had signed it with a black fountain pen and the ink had bled through the paper and blurred into a smudge. It’s difficult now to remember precisely what I thought of this invitation. I suppose I was flattered—although Brassard, who had somehow figured out what the letter was, made sure to inform me later that day that Smythe made a practice of inviting over each medical student who worked in his lab once (he emphasized the word) during his tenure—but oddly, I don’t recall being overly excited. Nor was I particularly worried. I had never quite understood how I had gotten the position in Smythe’s lab in the first place, and I knew for certain by then that it was not a place I would stay; lack of interest has a kind way of eliminating all potential nervousness.

  On Friday I arrived for dinner at Smythe’s house, a tall, narrow brownstone on the edge of the medical school campus. In the front was a Japanese red maple, now bare (it was early March), a holly bush with glossy, sharp leaves, and a clump of veined crocuses peering through their halo of mulch. The rest of the garden was bare, just plain wood chips. There was no harmony or apparent order to the plants’ arrangement; they just were. Inside, the house was very much the same way: in one corner of the entryway sat, incongruously, a Japanese tansu of blistering, puckered camphor. In another, just as incongruously, was an old-fashioned English secretary desk, the grain of the wood patterning its surface with satiny stripes. The rugs that covered the dusty floors were old Orientals, and I saw what looked like cracker crumbs speckling their tassels. The walls were hung with black shadowbox frames backed with black felt upon which were mounted lockets, their gold dull and whitish, and little scrimshaw carvings (a gnome, his crudely carved hands slapping together in a gesture of merriment; a ship, its sails pooching out unconvincingly), and cameos showing dreamy, loose-curled girls gazing off to the side, their expressions vacant. They were deeply idiosyncratic touches, and yet there was something furtive and unspecific about the house as well—it looked like the showroom for a second-rate auction house specializing in estate sales. There was nothing there that echoed who Smythe appeared to be, with his birchbark-colored hair and his lined face and his tall, upright walk and his magazine articles. Behind the frames, the walls were painted, each a different, strange color: puce and teal and that bright light green particular to unripened fruit. I had expected beiges and browns and perhaps some unobjectionable blues, everything neat and in order, not an eccentric’s house, for Smythe was not an eccentric.

  And yet everything around him that night seemed to argue that he was. Dinner, when it was at last served, was as ill-organized and haphazard as the house itself, as if assembled from whatever had been found in the refrigerator ten minutes before. There was tomato soup, thick as gravy and tasting strongly of ketchup; game hens, so undercooked that I could see the red arteries marbling the flesh; carrots and onions, so overcooked that they overflowed the tines of my fork with the gentlest press; another soup, this one seeming to consist purely of boiled onions and leeks and topped with a wet, suggestive coil of mustard; and for dessert what Smythe proudly told me were persimmons, sitting prim and Oriental on their blue-and-white chinoiserie plates but as hard as green plums—they tasted, when I was finally able to saw off a bite, like grass but sour, and it would be many years before I would be able to correct this impression.

  It was only the two of us at the table. Smythe sat at the head, nearest the kitchen, and I sat to his right. With each new course, he popped to his feet, disappeared through the pocket doors behind him, and came back bearing two plates in triumph. It had occurred to me, walking up the path to his house with a bottle of wine I’d thought to buy at the last minute, that he might be interested in interrogating me, that this might be a test of some sort. I was not worried about passing, but the thought of sitting down with Smythe—and, I assumed, his family—and being interviewed about my thoughts on various scientific quandaries of the day did not exactly fill me with excitement. But these had been wasted worries, for Smythe spent the entire evening speaking, from the time I entered the door and he took my coat with one hand and handed me a juice cup of brandy with the other (I have never cared for the taste of brandy, so flannelly on the teeth, and I tossed it into the shedding ficus in the foyer when Smythe went to fetch himself another cupful), throughout dinner, and over the glass of sher
ry he placed before me afterward, which I drank although I was longing for something cakey to neutralize the persimmon. The sherry glass was cut crystal and heavy, and I rotated it slowly in my fingers, watching the spangles of light it made against the wall opposite, which was a sickly, parchmentlike yellow.

  The evening began with small talk, which I was unaccustomed to and for which I had no talent. When I realized I had to say nothing, only to smile and nod from time to time, I was relieved. When we sat at the table—after standing for some time in the entryway, the two of us holding our plastic cups of brandy, while to my left lay a parlor, darkened and unused—he began to talk instead of his work. You would think, would you not, that in the more than two hours I listened to Smythe speak of his work I would learn something interesting, or that he would say something thoughtful, or at the very least provocative? But this was not to happen. He had the ability to talk at length on interesting subjects while somehow rendering them not only intensely uninteresting but completely opaque. “Sir,” I’d interject as Smythe cut eagerly into his fowl—he ate the entire meal with vigor and apparent satisfaction, but failed to notice that I had left most of mine untouched—“will you tell me a little about your research into viral mutation?” This was, after all, the basis of his entire theory, his life’s work. But he did not want to speak of his research; instead he spoke of the people who had impeded it. There was the dean, and the associate dean, and this colleague and that—he listed dozens of names, detailing to me what each had done and how now they had been humbled and made to look at him anew. The dean, he had heard, had rolled his eyes upon hearing about the Time magazine story. The associate dean had initially refused to give him the space he had wanted in Chase Hall, had tried to shunt him into a darker, inferior, smaller lab on the fifth floor. But he had prevailed, hadn’t he? He was without rancor, even jolly, as he told me these stories, onion-and-leek soup dripping from his spoon. He was not interested in discussing science. Still talking, he excused himself to the kitchen and came back with more soup, this time a blend of the two, which he swirled together with the handle of his spoon until it achieved a strange pasty consistency, and then he tucked his napkin into the collar of his shirt to protect his tie. He held it flat against his shirt with one hand and spooned up the soup with the other, murmuring his appreciation.

  Watching him, I wondered what the Turks would think of this display or if perhaps they already knew what Smythe was truly like, and if so, why did they remain with him, and how could they respect him? Had I underestimated the limits of their tolerance? Or was this an act that Smythe was performing only for me? Were the Turks and the junior residents crouched in the darkened parlor, their faces tight with held-back laughter, watching this bit of theater in which I was an unknowing and unwilling participant? Was this even Smythe’s house? Where was his wife—I knew he had one, and on his left ring finger he wore a thin golden circle—and wasn’t there something unnaturally still about these rooms? I kept thinking that if only I could find a reason to walk through the doors into the kitchen or cross the foyer into the living room, I would find the real house, one in which Smythe held forth articulately and behaved like the Great Man we all thought he was, and his pretty wife would serve a good meal, and his life would make sense to me and I would cease to feel like such an anthropologist in my own town, with the man who had hired me and invited me to dinner at his house.

  After we had drunk our sherry, he was silent for a moment, and I was able to speak at last. “Sir,” I asked, “why did you hire me?”

  “Ah,” he said, after a silence. “Why indeed.” He sighed and spun his glass in his fingers, and the reflections it made moved across his face like firefly light. “You are not a good student—you are dreamy and arrogant. Your professors find you ungovernable.” He said this all cheerfully, in the same pleasant tone in which he had recounted his enemies’ many failed plots against him. “But when they told me about you”—and here he turned and looked at me, and I could see for the first time his eyes, the pleats of skin that hung beneath them, his scleras as pink as those of the mice whose organs I harvested and shaved through sieves every day—“I suppose I remembered myself when I was your age. How desperately I wanted to escape, how little I felt I belonged, how much I craved my freedom, how much I craved my fame. We are alike, the two of us.”

  “I’m not like that,” I wanted to say, but I said nothing. He was drunk, I could now see. How long had he been like this? Had he been drunk when I first came in? I felt suddenly foolish, and childish, and embarrassed for myself. Why could I not see what was before me? What was the trick to understanding people that I alone seemed unable to possess? As I thought, Smythe was making strange noises, small gulping sounds. I thought he was choking, but when I hurried to him, I realized he was crying, his chin flat against the napkin still tucked into his shirt, his hands folded in his lap like a child’s. “Oh god,” he said. “Oh god.” I did not know what to do. My coat was on the chair next to me, where Smythe had placed it. I picked it up and fled.

  The following Monday I did not go into the lab. I did not go to any of my classes. Instead I stayed home and read, or looked at my atlas and made lists of places I wanted to see. I thought occasionally of what Smythe had said to me and decided he was wrong. I thought of him crying and felt pity for myself and disgust for him. For meals, I made my favorite snack, hot oatmeal into which I stirred raw eggs, until I realized that it was the sort of strange concoction Smythe might serve. I was terrified that I might become him, although it was not until some years later—about the time, in fact, I discovered what a persimmon should truly taste like—that I was able to define why: that worse than his poor science, the flimsy scholarship, was his small, inexplicable life alone in that strange house, with no one around to distract him from the meagerness of his own existence. It startled me to learn this about myself, that I had such petty, poor fears, that I had come to think in such trite and soft ways.

  After a few days of my moping, the medical school secretary called, asking snippily if I was planning on returning to classes, followed by Brassard, who told me in his sniffing way that I had potentially ruined Parton’s experiment and oughtn’t bother returning. When I hung up, I was relieved, for in the space of my dinner with Smythe the lab had come to seem a sort of trap, a sort of place where I would become like him, holding my theory tightly to me, idealess, terrified of the inevitable day when I would be proved an imposter. Or at least this is what I told myself I feared. Now I had been not just released but told I was inappropriate, that I would never become one of them, and their words, their dismissal, left me shaky with joy. I was safe, I thought, and for some time, for a long time, I was.

  The next day I returned to my classes. My professors—some of whom were quite close to the Turks—seemed to have heard that I was no longer with Smythe’s lab and, surprisingly, treated me better than they had before, although I was still nobody exceptional. But I was careful not to feel resentful about this, as I might have before. I thought of Smythe—“But now they’re coming back to me, now they’re giving me what I want”—and cringed. For the next year I attended classes and sat silently in the lecture halls, determined not to make myself into something more significant than I really was. It was my first lesson in humility, in the lab or in life.16

  III.

  One of the attractions of medical school for the unimaginative (or, if I am to be more charitable, to the less dreamily inclined) is certainly the lack of choices it offers. Of course, a doctor, whether he works with patients or alone, with tissues, must make dozens of decisions within a given day, but the larger questions—the ones about what you must do next in life—are answered for you. Indeed, you need never think about what the next year will bring, because for many years the path is laid before you, and it is only your duty to follow it. College leads to medical school, which leads to internships and residencies, which leads perhaps to fellowships, then to an appointment or a private practice or a job in a hospital or a g
roup. It is this way now, and it was this way when I was in school as well.

  By the January of my last year in medical school, I was feeling anxious. It was not a familiar sensation, and not a welcome one, either. I had no intention of working with patients, and so while my classmates interviewed for internships, I sat in my room like a hunk of wood, waiting for my future to resolve itself. It embarrasses me now, how inactive I was, how I allowed ignorance and naïveté to stymie me, but at the time it seemed a no more or less effective way of answering a future I could not even begin to imagine for myself.

  A few months into this paralysis, probably in March or so—a year after my disastrous dinner with Smythe, in fact—one of my instructors, a man named Adolphus Sereny,17 with whom I was completing my surgical rotation, asked me to come see him in his office at the hospital one day.