The next generation of genetic engineering will make pigs with good fat look like child’s play. Geneticists have managed not merely to extend sixfold the average life expectancy of worms, but also to engineer genius mice that display much-improved memory and learning skills.7 Voles are small, stout rodents resembling mice, and most varieties of voles are promiscuous. But there is one species in which boy and girl voles form lasting and monogamous relationships. Geneticists claim to have isolated the genes responsible for vole monogamy. If the addition of a gene can turn a vole Don Juan into a loyal and loving husband, are we far off from being able to genetically engineer not only the individual abilities of rodents (and humans), but also their social structures?8
The Return of the Neanderthals
But geneticists do not only want to transform living lineages. They aim to revive extinct creatures as well. And not just dinosaurs, as in the Hollywood blockbuster Jurassic Park. A team of Russian, Japanese and Korean scientists has recently mapped the genome of ancient mammoths, found frozen in the Siberian ice. They now plan to take a fertilised egg-cell of a present-day elephant, replace the elephantine DNA with a reconstructed mammoth DNA, and implant the egg in the womb of an elephant. After about twenty-two months, they expect the first mammoth in 5,000 years to be born.9
But why stop at mammoths? Professor George Church of Harvard University recently suggested that, with the completion of the Neanderthal Genome Project, we can now implant reconstructed Neanderthal DNA into a Sapiens ovum, thus producing the first Neanderthal child in 30,000 years. Church claimed that he could do the job for a paltry $30 million. Several women have already volunteered to serve as surrogate mothers.10
What do we need Neanderthals for? Some argue that if we could study live Neanderthals, we could answer some of the most nagging questions about the origins and uniqueness of Homo sapiens. By comparing a Neanderthal to a Homo sapiens brain, and mapping out where their structures differ, perhaps we could identify what biological change produced consciousness as we experience it. There’s an ethical reason, too – some have argued that if Homo sapiens was responsible for the extinction of the Neanderthals, it has a moral duty to resurrect them. And having some Neanderthals around might be useful. Lots of industrialists would be glad to pay one Neanderthal to do the menial work of two Sapiens.
But why stop even at Neanderthals? Why not go back to God’s drawing board and design a better Sapiens? The abilities, needs and desires of Homo sapiens have a genetic basis, and the Sapiens genome is no more complex than that of voles and mice. (The mouse genome contains about 2.5 billion nucleobases, the Sapiens genome about 2.9 billion bases – meaning the latter is only 14 per cent larger.)11 In the medium range – perhaps in a few decades – genetic engineering and other forms of biological engineering might enable us to make far-reaching alterations not only to our physiology, immune system and life expectancy, but also to our intellectual and emotional capacities. If genetic engineering can create genius mice, why not genius humans? If it can create monogamous voles, why not humans hard-wired to remain faithful to their partners?
The Cognitive Revolution that turned Homo sapiens from an insignificant ape into the master of the world did not require any noticeable change in physiology or even in the size and external shape of the Sapiens brain. It apparently involved no more than a few small changes to internal brain structure. Perhaps another small change would be enough to ignite a Second Cognitive Revolution, create a completely new type of consciousness, and transform Homo sapiens into something altogether different.
True, we still don’t have the acumen to achieve this, but there seems to be no insurmountable technical barrier preventing us from producing superhumans. The main obstacles are the ethical and political objections that have slowed down research on humans. And no matter how convincing the ethical arguments may be, it is hard to see how they can hold back the next step for long, especially if what is at stake is the possibility of prolonging human life indefinitely, conquering incurable diseases, and upgrading our cognitive and emotional abilities.
What would happen, for example, if we developed a cure for Alzheimer’s disease that, as a side benefit, could dramatically improve the memories of healthy people? Would anyone be able to halt the relevant research? And when the cure is developed, could any law enforcement agency limit it to Alzheimer’s patients and prevent healthy people from using it to acquire super-memories?
It’s unclear whether bioengineering could really resurrect the Neanderthals, but it would very likely bring down the curtain on Homo sapiens. Tinkering with our genes won’t necessarily kill us. But we might fiddle with Homo sapiens to such an extent that we would no longer be Homo sapiens.
Bionic Life
There is another new technology which could change the laws of life: cyborg engineering. Cyborgs are beings which combine organic and inorganic parts, such as a human with bionic hands. In a sense, nearly all of us are bionic these days, since our natural senses and functions are supplemented by devices such as eyeglasses, pacemakers, orthotics, and even computers and mobile phones (which relieve our brains of some of their data storage and processing burdens). We stand poised on the brink of becoming true cyborgs, of having inorganic features that are inseparable from our bodies, features that modify our abilities, desires, personalities and identities.
The Defense Advanced Research Projects Agency (DARPA), a US military research agency, is developing cyborgs out of insects. The idea is to implant electronic chips, detectors and processors in the body of a fly or cockroach, which will enable either a human or an automatic operator to control the insect’s movements remotely and to absorb and transmit information. Such a fly could be sitting on the wall at enemy headquarters, eavesdrop on the most secret conversations, and if it isn’t caught first by a spider, could inform us exactly what the enemy is planning.12 In 2006 the US Naval Undersea Warfare Center reported its intention to develop cyborg sharks, declaring, ‘NUWC is developing a fish tag whose goal is behaviour control of host animals via neural implants.’ The developers hope to identify underwater electromagnetic fields made by submarines and mines, by exploiting the natural magnetic detecting capabilities of sharks, which are superior to those of any man-made detectors.13
Sapiens, too, are being turned into cyborgs. The newest generation of hearing aids are sometimes referred to as ‘bionic ears’. The device consists of an implant that absorbs sound through a microphone located in the outer part of the ear. The implant filters the sounds, identifies human voices, and translates them into electric signals that are sent directly to the central auditory nerve and from there to the brain.14
Retina Implant, a government-sponsored German company, is developing a retinal prosthesis that may allow blind people to gain partial vision. It involves implanting a small microchip inside the patient’s eye. Photocells absorb light falling on the eye and transform it into electrical energy, which stimulates the intact nerve cells in the retina. The nervous impulses from these cells stimulate the brain, where they are translated into sight. At present the technology allows patients to orientate themselves in space, identify letters, and even recognise faces.15
Jesse Sullivan, an American electrician, lost both arms up to the shoulder in a 2001 accident. Today he uses two bionic arms, courtesy of the Rehabilitation Institute of Chicago. The special feature of Jesse’s new arms is that they are operated by thought alone. Neural signals arriving from Jesse’s brain are translated by micro-computers into electrical commands, and the arms move. When Jesse wants to raise his arm, he does what any normal person unconsciously does – and the arm rises. These arms can perform a much more limited range of movements than organic arms, but they enable Jesse to carry out simple daily functions. A similar bionic arm has recently been outfitted for Claudia Mitchell, an American soldier who lost her arm in a motorcycle accident. Scientists believe that we will soon have bionic arms that will not only move when willed to move, but will also be able to transmit signals back
to the brain, thereby enabling amputees to regain even the sensation of touch!16
48. Jesse Sullivan and Claudia Mitchell holding hands. The amazing thing about their bionic arms is that they are operated by thought.
{© ImageBank/Getty Images Israel.}
At present these bionic arms are a poor replacement for our organic originals, but they have the potential for unlimited development. Bionic arms, for example, can be made far more powerful than their organic kin, making even a boxing champion feel like a weakling. Moreover, bionic arms have the advantage that they can be replaced every few years, or detached from the body and operated at a distance.
Scientists at Duke University in North Carolina have recently demonstrated this with rhesus monkeys whose brains have been implanted with electrodes. The electrodes gather signals from the brain and transmit them to external devices. The monkeys have been trained to control detached bionic arms and legs through thought alone. One monkey, named Aurora, learned to thought-control a detached bionic arm while simultaneously moving her two organic arms. Like some Hindu goddess, Aurora now has three arms, and her arms can be located in different rooms – or even cities. She can sit in her North Carolina lab, scratch her back with one hand, scratch her head with a second hand, and simultaneously steal a banana in New York (although the ability to eat a purloined fruit at a distance remains a dream). Another rhesus monkey, Idoya, won world fame in 2008 when she thought-controlled a pair of bionic legs in Kyoto, Japan, from her North Carolina chair. The legs were twenty times Idoya’s weight.17
Locked-in syndrome is a condition in which a person loses all or nearly all her ability to move any part of her body, while her cognitive abilities remain intact. Patients suffering from the syndrome have up till now been able to communicate with the outside world only through small eye movements. However, a few patients have had brain-signal-gathering electrodes implanted in their brains. Efforts are being made to translate such signals not merely into movements but also into words. If the experiments succeed, locked-in patients could finally speak directly with the outside world, and we might eventually be able to use the technology to read other people’s minds.18
Yet of all the projects currently under development, the most revolutionary is the attempt to devise a direct two-way brain-computer interface that will allow computers to read the electrical signals of a human brain, simultaneously transmitting signals that the brain can read in turn. What if such interfaces are used to directly link a brain to the Internet, or to directly link several brains to each other, thereby creating a sort of Inter-brain-net? What might happen to human memory, human consciousness and human identity if the brain has direct access to a collective memory bank? In such a situation, one cyborg could, for example, retrieve the memories of another – not hear about them, not read about them in an autobiography, not imagine them, but directly remember them as if they were his own. Or her own. What happens to concepts such as the self and gender identity when minds become collective? How could you know thyself or follow your dream if the dream is not in your mind but in some collective reservoir of aspirations?
Such a cyborg would no longer be human, or even organic. It would be something completely different. It would be so fundamentally another kind of being that we cannot even grasp the philosophical, psychological or political implications.
Another Life
The third way to change the laws of life is to engineer completely inorganic beings. The most obvious examples are computer programs and computer viruses that can undergo independent evolution.
The field of genetic programming is today one of the most interesting spots in the computer science world. It tries to emulate the methods of genetic evolution. Many programmers dream of creating a program that could learn and evolve completely independently of its creator. In this case, the programmer would be a primum mobile, a first mover, but his creation would be free to evolve in directions neither its maker nor any other human could ever have envisaged.
A prototype for such a program already exists – it’s called a computer virus. As it spreads through the Internet, the virus replicates itself millions upon millions of times, all the while being chased by predatory antivirus programs and competing with other viruses for a place in cyberspace. One day when the virus replicates itself a mistake occurs – a computerised mutation. Perhaps the mutation occurs because the human engineer programmed the virus to make occasional random replication mistakes. Perhaps the mutation was due to a random error. If, by chance, the modified virus is better at evading antivirus programs without losing its ability to invade other computers, it will spread through cyberspace. If so, the mutants will survive and reproduce. As time goes by, cyberspace would be full of new viruses that nobody engineered, and that undergo non-organic evolution.
Are these living creatures? It depends on what you mean by ‘living creatures’. They have certainly been produced by a new evolutionary process, completely independent of the laws and limitations of organic evolution.
Imagine another possibility – suppose you could back up your brain to a portable hard drive and then run it on your laptop. Would your laptop be able to think and feel just like a Sapiens? If so, would it be you or someone else? What if computer programmers could create an entirely new but digital mind, composed of computer code, complete with a sense of self, consciousness and memory? If you ran the program on your computer, would it be a person? If you deleted it could you be charged with murder?
We might soon have the answer to such questions. The Human Brain Project, founded in 2005, hopes to recreate a complete human brain inside a computer, with electronic circuits in the computer emulating neural networks in the brain. The project’s director has claimed that, if funded properly, within a decade or two we could have an artificial human brain inside a computer that could talk and behave very much as a human does. If successful, that would mean that after 4 billion years of milling around inside the small world of organic compounds, life will suddenly break out into the vastness of the inorganic realm, ready to take up shapes beyond our wildest dreams. Not all scholars agree that the mind works in a manner analogous to today’s digital computers – and if it doesn’t, present-day computers would not be able to simulate it. Yet it would be foolish to categorically dismiss the possibility before giving it a try. In 2013 the project received a grant of €1 billion from the European Union.19
The Singularity
Presently, only a tiny fraction of these new opportunities have been realised. Yet the world of 2014 is already a world in which culture is releasing itself from the shackles of biology. Our ability to engineer not merely the world around us, but above all the world inside our bodies and minds, is developing at breakneck speed. More and more spheres of activity are being shaken out of their complacent ways. Lawyers need to rethink issues of privacy and identity; governments are faced with rethinking matters of health care and equality; sports associations and educational institutions need to redefine fair play and achievement; pension funds and labour markets should readjust to a world in which sixty might be the new thirty. They must all deal with the conundrums of bioengineering, cyborgs and inorganic life.
Mapping the first human genome required fifteen years and $3 billion. Today you can map a person’s DNA within a few weeks and at the cost of a few hundred dollars.20 The era of personalised medicine – medicine that matches treatment to DNA – has begun. The family doctor could soon tell you with greater certainty that you face high risks of liver cancer, whereas you needn’t worry too much about heart attacks. She could determine that a popular medication that helps 92 per cent of people is useless to you, and you should instead take another pill, fatal to many people but just right for you. The road to near-perfect medicine stands before us.
However, with improvements in medical knowledge will come new ethical conundrums. Ethicists and legal experts are already wrestling with the thorny issue of privacy as it relates to DNA. Would insurance companies be entitled to ask for our
DNA scans and to raise premiums if they discover a genetic tendency to reckless behaviour? Would we be required to fax our DNA, rather than our CV, to potential employers? Could an employer favour a candidate because his DNA looks better? Or could we sue in such cases for ‘genetic discrimination’? Could a company that develops a new creature or a new organ register a patent on its DNA sequences? It is obvious that one can own a particular chicken, but can one own an entire species?
Such dilemmas are dwarfed by the ethical, social and political implications of the Gilgamesh Project and of our potential new abilities to create superhumans. The Universal Declaration of Human Rights, government medical programmes throughout the world, national health insurance programmes and national constitutions worldwide recognise that a humane society ought to give all its members fair medical treatment and keep them in relatively good health. That was all well and good as long as medicine was chiefly concerned with preventing illness and healing the sick. What might happen once medicine becomes preoccupied with enhancing human abilities? Would all humans be entitled to such enhanced abilities, or would there be a new superhuman elite?
Our late modern world prides itself on recognising, for the first time in history, the basic equality of all humans, yet it might be poised to create the most unequal of all societies. Throughout history, the upper classes always claimed to be smarter, stronger and generally better than the underclass. They were usually deluding themselves. A baby born to a poor peasant family was likely to be as intelligent as the crown prince. With the help of new medical capabilities, the pretensions of the upper classes might soon become an objective reality.
This is not science fiction. Most science-fiction plots describe a world in which Sapiens – identical to us – enjoy superior technology such as light-speed spaceships and laser guns. The ethical and political dilemmas central to these plots are taken from our own world, and they merely recreate our emotional and social tensions against a futuristic backdrop. Yet the real potential of future technologies is to change Homo sapiens itself, including our emotions and desires, and not merely our vehicles and weapons. What is a spaceship compared to an eternally young cyborg who does not breed and has no sexuality, who can share thoughts directly with other beings, whose abilities to focus and remember are a thousand times greater than our own, and who is never angry or sad, but has emotions and desires that we cannot begin to imagine?